Technology

Focused sound.
Visible precision.

SONIRE is developing a next-generation ultrasound-guided HIFU therapy system designed around treatment visibility, heating efficiency, multi-point irradiation and precise positioning.

HIFU mechanism

Treat from outside the body. Focus inside it.

A transducer generates ultrasound outside the body and concentrates it at a target. As HIFU propagates through tissue, absorbed acoustic energy is converted to heat at the focal region.

SONIRE HIFU treatment mechanism
Potential advantages

The treatment model SONIRE is pursuing.

SONIRE’s current site highlights three HIFU characteristics: minimal invasiveness, the possibility of one-day treatment, and repeatability without radiation exposure.

Minimally invasive

Focused energy is delivered without a surgical incision.

One-day treatment

SONIRE’s published materials describe an outpatient treatment model.

Repeatable

Unlike radiation, HIFU itself does not use ionizing radiation.

SONIRE approach

Cavitation is not just an effect. It is part of the interface.

SONIRE creates cavitation bubbles with ultrasound pulses. Its public technology description says those bubbles both enhance absorption of acoustic energy and help visualize the treatment area under ultrasound guidance.

Cavitation bubble clouds and ultrasound guidance
01

HIFU interference reduction.

The system is designed to reduce interference between treatment HIFU and ultrasound imaging so clinicians can maintain a useful field of view during treatment.

HIFU interference reduction concept
02

Visualization using cavitation bubbles.

The current SONIRE site includes treatment-visualization motion content. Here the concept becomes a full-width moving field rather than a tiny embedded clip.

Live treatment visualization study
03

Cavitation-enhanced heating.

SONIRE uses the absorption of ultrasound energy by cavitation bubbles to enhance heating efficiency.

SONIRE cavitation enhanced heating comparison
04

Multi-channel, multi-point irradiation.

Rapid multi-focus scanning is intended to increase treatment efficiency compared with a single-focus approach.

Single-focus and multi-focus HIFU comparison
05

Robot-assisted positioning.

Precision drive mode supports millimeter-scale irradiation control while manual mode is designed for intuitive positioning.

mm
precision drive
Manual
intuitive positioning
Suizenji platformSONIRE Suizenji therapy platform
System architecture

Guidance + irradiation + robotics.

SONIRE’s public 2026 materials describe the platform as combining real-time imaging guidance with noise cancellation, cavitation bubble visualization, robot-assisted positioning and rapid multi-focus scanning.

See clinical development
Official SONIRE video

The science in motion.

This official SONIRE one-minute film is given a dedicated media stage with a deliberate play interaction and no visual clutter around it.

Official film

Focused ultrasound, explained by SONIRE.

Next

Technology becomes meaningful when the evidence catches up.

See how SUNRISE-I, SUNRISE-II and SONIRE’s FDA Breakthrough Device designation fit together.

Clinical development